Describe how griseofulvin works as an antifungal agent.

Study for the Pharmacology Antifungal Agents Test. Use flashcards and multiple choice questions with hints and explanations. Ace your exam!

Griseofulvin functions as an antifungal agent primarily by inhibiting fungal cell mitosis. It achieves this by binding to microtubules, which are critical components of the mitotic spindle necessary for cell division. This action disrupts the formation of the mitotic spindle during cell division, effectively halting the proliferation of the fungi. As a result, the fungal cells are unable to complete the process of mitosis, leading to a reduction in their numbers and ultimately aiding in the resolution of the fungal infection.

The other mechanisms of action mentioned in the options, such as inhibiting cell wall synthesis or interfering with protein synthesis, do not accurately represent the specific action of griseofulvin. Additionally, blocking ergosterol synthesis is characteristic of other antifungal agents, such as azoles or polyenes, but not griseofulvin. Understanding the precise mechanism of action for antifungal agents is crucial for effective treatment strategies and addressing various fungal infections.

Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy