In preparing to educate a client starting on voriconazole, what point should the nurse include?

Voriconazole is an antifungal medication that requires careful consideration of drug interactions due to its effects on the cytochrome P450 enzyme system. Many drugs are metabolized through this system, and voriconazole can either enhance or inhibit the metabolism of these medications. This interaction can lead to increased toxicity or decreased efficacy of either voriconazole or the interacting drug. Patients need to be educated about the importance of informing healthcare providers of all medications, including over-the-counter drugs and supplements, they are taking to prevent adverse effects or therapeutic failures.

Other options present points that, while relevant, do not highlight the critical nature of drug interactions. The form of administration does not inherently define effectiveness between oral and injectable routes, as both can be effective when used appropriately in clinical settings. Additionally, voriconazole can be taken without regard to food, meaning that it does not affect absorption significantly. Lastly, voriconazole is generally administered on a daily basis, not every other day, which is essential for maintaining appropriate therapeutic levels in the body for its antifungal effects.