What effect does terbinafine have on dermatophytes?

Terbinafine is an antifungal agent predominantly used to treat infections caused by dermatophytes, which are fungi that cause conditions like athlete's foot and ringworm. The mechanism by which terbinafine exerts its antifungal effect is through the inhibition of ergosterol synthesis. Ergosterol is a crucial component of the fungal cell membrane, essential for maintaining its integrity and functionality. By preventing the synthesis of ergosterol, terbinafine disrupts the formation of the cell membrane, ultimately leading to cell death and effectively eliminating the dermatophyte infection.

This action specifically targets the fungal cells while having minimal effects on human cells, as human cell membranes do not contain ergosterol but instead contain cholesterol, making terbinafine a selective and effective treatment for mycotic infections. Other options presented would not accurately reflect terbinafine's mechanism of action in combating dermatophyte pathogens.