What is a common adverse effect associated with azole antifungals?

Azole antifungals are a class of medications commonly used to treat fungal infections, and nausea and vomiting are well-known side effects associated with their use. This gastrointestinal discomfort stems from the way azole antifungals can affect the stomach lining and gastrointestinal motility.

Patients may experience nausea due to the way these medications interact with the body's metabolism, and this can lead to vomiting as a secondary effect. Monitoring for these symptoms is important in clinical practice, as they can affect patient compliance with the treatment regimen. Other adverse effects are also possible, but nausea and vomiting are particularly common and significant in the context of azole antifungals, making them essential for healthcare providers to communicate to their patients.

In contrast, while adverse effects like cardiac arrhythmias, visual disturbances, and skin rashes can occur with certain medications, they are less characteristic of the azole class and are not the most frequently reported side effects.