What is the primary aspect that the nurse should monitor in a client receiving amphotericin B?

In a client receiving amphotericin B, the primary aspect to monitor is the serum electrolytes, particularly potassium and magnesium levels. Amphotericin B is known for causing significant electrolyte imbalances, which can lead to complications such as hypokalemia (low potassium levels) and hypomagnesemia (low magnesium levels). These imbalances can affect cardiac function and neuromuscular stability, making electrolyte monitoring crucial.

Although monitoring the complete blood count (CBC) is important to assess for potential hematological side effects, the more acute concern with amphotericin B relates to its nephrotoxic effects and the resulting impacts on serum electrolytes. Regular checks of liver function tests and blood glucose levels may also play roles in patient management, but they are not as immediate in relation to the known side effects of amphotericin B as serum electrolytes. Therefore, the focus should be on closely monitoring electrolyte levels to mitigate risks associated with this antifungal treatment.