What is the primary use of nystatin in antifungal therapy?

Nystatin is primarily used for the treatment of oropharyngeal candidiasis, commonly known as thrush. This antifungal agent is particularly effective against Candida species, which are the most prevalent fungi responsible for this condition. Nystatin works by binding to ergosterol in fungal cell membranes, causing cell leakage and ultimately leading to cell death.

While nystatin can be used for skin infections caused by Candida, its specific formulation and administration route make it especially suitable for treating oropharyngeal candidiasis. The drug is typically administered as an oral suspension, allowing it to directly target the mucosal surfaces of the mouth and throat where the fungus thrives. Therefore, its effectiveness in treating oropharyngeal candidiasis underscores its primary use in antifungal therapy.