What laboratory test is commonly monitored with amphotericin B use?

Amphotericin B is an antifungal agent that can have significant nephrotoxic effects, meaning it can potentially cause harm to the kidneys. Therefore, serum creatinine levels are monitored to assess renal function during treatment with this medication. An increase in serum creatinine can indicate a decline in the kidneys' ability to filter waste from the blood, which is a common side effect of amphotericin B therapy. Regular monitoring allows healthcare providers to detect any adverse effects early, manage them appropriately, and adjust the treatment regimen if necessary to prevent further kidney damage.

While other options, such as white blood cell count, hemoglobin levels, and liver function tests, are important in certain clinical contexts, they are not specifically monitored as closely in relation to the use of amphotericin B compared to serum creatinine levels.