Which antifungal agent has activity against both mold and yeast?

The antifungal agent that is known for its activity against both mold and yeast is Itraconazole. Itraconazole belongs to the triazole class of antifungals and offers broad-spectrum activity. It is particularly effective against a variety of fungal pathogens, including several species of yeasts such as Candida and molds such as Aspergillus.

This agent functions by inhibiting the fungal enzyme lanosterol 14-alpha-demethylase, which is crucial for the synthesis of ergosterol, an essential component of the fungal cell membrane. By disrupting ergosterol production, Itraconazole compromises the integrity and functionality of the cell membrane, leading to cell death.

While other antifungals may provide activity against either yeast or mold, Itraconazole is distinctive in its ability to effectively target both categories of fungi. For example, Fluconazole primarily targets yeasts and has some limited mold activity, but it is not as broad-spectrum as Itraconazole. Amphotericin B is effective against a wide range of fungi but is generally used more for severe infections and is not categorized strictly as a triazole. Caspofungin, on the other hand, is more specific for certain molds and is less effective against ye