Which condition would not typically necessitate antifungal treatment?

Severe headache typically does not necessitate antifungal treatment because headaches can arise from a multitude of causes that are unrelated to fungal infections. Fungal infections generally present with specific symptoms and signs associated with their respective conditions, such as vaginal candidiasis, which is an infection caused by Candida species, and systemic fungal infections that affect internal organs. Skin fungal infections also have definitive clinical presentations, such as ringworm or athlete's foot, which are treated effectively with antifungal medications.

In contrast, a severe headache might indicate an unrelated issue, like tension, migraines, or other neurological conditions, and does not reflect an underlying fungal infection that would require antifungal therapy. Therefore, this scenario does not warrant the use of antifungal agents, making it the correct choice in this context.