Which of the following is a common side effect of ketoconazole?

Gynecomastia is indeed a common side effect associated with ketoconazole. This occurs due to ketoconazole's ability to inhibit the synthesis of sex hormones, including testosterone. As a result, an imbalance in hormone levels can lead to the development of breast tissue in males. This side effect is particularly significant because it not only affects physical appearance but can also have psychological impacts on the individual.

In addition to gynecomastia, ketoconazole can have various other side effects, but the specific mechanism underlying its hormonal effects makes gynecomastia a well-documented and notable risk concerning its use. It’s important for healthcare providers to inform patients about this potential side effect, especially in males, to prepare them for any changes they might observe while on the medication.