Why is it important to consider the severity of a fungal infection when selecting treatment?

Considering the severity of a fungal infection when selecting treatment is crucial because it directly determines the route of administration for the antifungal therapy. More severe infections may require systemic treatment, which is typically administered intravenously or orally to ensure adequate drug levels in the bloodstream. This is essential for effectively reaching and penetrating deep tissues, where the fungal agents may reside. In contrast, less severe infections may be appropriately treated with topical agents, which can be applied directly to the affected area and may not necessitate the use of systemic medication.

This understanding ensures that the therapy is tailored to the specific clinical scenario, maximizing the likelihood of successful eradication of the fungi while minimizing adverse effects associated with inappropriate or insufficient treatment routes.